Customize Website Template

I have a website template that I'd like to have customized. I've already altered the PhotoShop files but do not know how to work with slices. Essentially, I need two pages made - one for the home page, and one for inside pages. If they are to be made into Dreamweaver templates (this is the program I work in), I will need pretty much all areas to be editable regions so I can add and change, when necessary. I just can't for the life of me, figure out these darned slices! I think it's going to be a relatively quick and easy project, and I'd like it to be completed by the weekend, if possible. Thanks, Pam