Document management software (DMS)

I'm developing a web application for a medical office. The goal is a paperless office but of course this is not a reality. Thus, I'm looking to develop an application to handle documents as a separate project. The files will be stored in the cloud and synchronized to all machines via OneDrive or Dropbox so the files will also be stored locally on the user's machine. The medical application is being developed in CakePHP so I presume this will need to be developed with the same??? Some developers have recommended a web application while others have suggested a desktop application (since the files manipulated will be local) and then integrated with the EMR web project. Further details about the project are included in the download link. Start with the Word document which details the functionality. This program is essentially a file explorer with enhanced functionality to work like Paperport. Link: [login to view URL]